Fig. 6From: 3D reconstruction of biological structures: automated procedures for alignment and reconstruction of multiple tilt series in electron tomographyTomogram views (XY, YZ, and XZ) of a 5-nm gold particle with respect to the number of tilt series N. A FBP is used. B wSIRT is used. While the image quality improves as N increases, the reconstruction still remain impaired by artifacts caused by the missing pyramid problem (equivalent to a missing cone problem when \(N\rightarrow \infty\)). Note artifacts are attenuated for wSIRT (50 iterations and \(\alpha =2\)) compared to FBPBack to article page