Table 1 A summary of relevant differences between imaging in broad beam mode and with a focused electron beam

Dose rates

1–10 000 e/Ųs

(6–600) * 1,000,000 e/Ųs

Time constants (image acquisition)

0.1–10 s

1–100 μs per pixel

Minimal spread in beam direction (highest resolution)

<7 Å

~40 Å

Electron detection

Real space

Reciprocal space

Acquisition process

Parallel

Serial

Visibility

Entire sample thickness

Thickness slices (resolution dependent)