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Table 1 A summary of relevant differences between imaging in broad beam mode and with a focused electron beam

From: Detecting structural variances of Co3O4 catalysts by controlling beam-induced sample alterations in the vacuum of a transmission electron microscope

Relevant differences Broad beam (preferred in biology) Focused beam
Dose rates 1–10 000 e/Å2s (6–600) * 1,000,000 e/Å2s
Time constants (image acquisition) 0.1–10 s 1–100 μs per pixel
Minimal spread in beam direction (highest resolution) <7 Å ~40 Å
Electron detection Real space Reciprocal space
Acquisition process Parallel Serial
Visibility Entire sample thickness Thickness slices (resolution dependent)